Birmingham, West Midlands, England News
Rift with McLeish denied by Birmingham chairman
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Cigarette smoke may cause inflammation through a new chemical pathway
Washington, Sept 3 ANI: Cigarette smoke causes a key enzyme that regulates the body's response to inflammation, to shut off, according to a new study.esearchers at University of Alabama at Birmingham found that smoke causes the enzyme to shut down white blood cells following a successful response to inflammation. The study also found a previously unknown substrate of the enzyme, which recruits white blood cells that attack the cause of the inflammation. "We found, however, that cigarette smoke inhibited LTA4H, preventing it from shutting down PGP," said J. Edwin Blalock. Blalock said PGP is a biomarker for several lung diseases that feature chronic inflammation, such as chronic obstructive pulmonary disease COPD and cystic fibrosis. The study also details a dual role played by the enzyme; when contained within a cell, it has a pro-inflammatory job. However, when the enzyme is found outside of the cell when the cell it resides in dies, for example its role switches to an anti-inflammatory one. "This dual role could have important ramifications for the design of new anti-inflammatory drugs that target LTA4H," said Blalock. The findings are published online today at Science Express. ANI
Washington, Sept 3 ANI: Cigarette smoke causes a key enzyme that regulates the body's response to inflammation, to shut off, according to a new study.esearchers at University of Alabama at Birmingham found that smoke causes the enzyme to shut down white blood cells following a successful response to inflammation. The study also found a previously unknown substrate of the enzyme, which recruits white blood cells that attack the cause of the inflammation. "We found, however, that cigarette smoke inhibited LTA4H, preventing it from shutting down PGP," said J. Edwin Blalock. Blalock said PGP is a biomarker for several lung diseases that feature chronic inflammation, such as chronic obstructive pulmonary disease COPD and cystic fibrosis. The study also details a dual role played by the enzyme; when contained within a cell, it has a pro-inflammatory job. However, when the enzyme is found outside of the cell when the cell it resides in dies, for example its role switches to an anti-inflammatory one. "This dual role could have important ramifications for the design of new anti-inflammatory drugs that target LTA4H," said Blalock. The findings are published online today at Science Express. ANI
Birmingham vice-chairman backtracks on McLeish
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McLeish calms Birmingham expectations
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Birmingham land Hleb on season's loan
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Davis puts injury in rearview mirror
HATTIESBURG — It was 11 months ago that Austin Davis’ dazzling sophomore season at Southern Miss came to end at Legion Field against Alabama-Birmingham.
HATTIESBURG — It was 11 months ago that Austin Davis’ dazzling sophomore season at Southern Miss came to end at Legion Field against Alabama-Birmingham.
Cricket scandal could hit flood aid for Pakistan
The match fixing scandal could hit aid for victims of floods that have ravaged Pakistan, feared a British MP who added that it was "absolutely the worst thing that could have happened now". Khalid Mahmood, a Labour MP from Perry Barr in Birmingham, said: "It's very damaging to Pakistan, especially to the relief effort." "It's very negative and absolutely the worst thing that could have happened now. A lot of people of Pakistani origin are hugely disappointed to the extent that they don't want to have any association with the cricket team any more. They feel hugely let down and disgraced," Daily Express Tuesday quoted him as saying. Mazhar Majeed, a 35-year-old agent, was caught on videotape accepting 150,000 pounds in a sting operation conducted by The News of the World NOTW tabloid. Three Pakistani players - captain Salman Butt, Mohammad Asif and Mohammad Amir - are charged with under-performing in the fourth Test match between England and Pakistan. The MP said that people will think twice before giving cash. "It will have a knock-on effect. "The people of Pakistan will have many more troubles heading their way because of the flooding, through disease and famine, so they are in desperate need of help. But such a disgraceful, negative story will cancel out an awful lot of good work that has been done."
The match fixing scandal could hit aid for victims of floods that have ravaged Pakistan, feared a British MP who added that it was "absolutely the worst thing that could have happened now". Khalid Mahmood, a Labour MP from Perry Barr in Birmingham, said: "It's very damaging to Pakistan, especially to the relief effort." "It's very negative and absolutely the worst thing that could have happened now. A lot of people of Pakistani origin are hugely disappointed to the extent that they don't want to have any association with the cricket team any more. They feel hugely let down and disgraced," Daily Express Tuesday quoted him as saying. Mazhar Majeed, a 35-year-old agent, was caught on videotape accepting 150,000 pounds in a sting operation conducted by The News of the World NOTW tabloid. Three Pakistani players - captain Salman Butt, Mohammad Asif and Mohammad Amir - are charged with under-performing in the fourth Test match between England and Pakistan. The MP said that people will think twice before giving cash. "It will have a knock-on effect. "The people of Pakistan will have many more troubles heading their way because of the flooding, through disease and famine, so they are in desperate need of help. But such a disgraceful, negative story will cancel out an awful lot of good work that has been done."
Birmingham complete Jiranek signing
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Hleb joins Birmingham on loan
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Chile winger Beausejour joins Birmingham
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